Alazraqui has since performed several voices for Nickelodeon cartoons, including Rocko on Rocko's Modern Life, as well as Denzel Q. Crocker and Juandissimo Magnifico on The Fairly OddParents, Winslow T. Oddfellow and Lube on CatDog, and additional voices on Angry Beavers and KaBlam!. Alazraqui also voiced several additional voices for the Cartoon Network shows, Cow and Chicken and I Am Weasel during their runs in the mid-late 1990s. He also voiced the titular protagonist of the first game in the Spyro the Dragon series, the Taco Bell chihuahua, Rikochet in the first two seasons of Mucha Lucha and Mr. Weed (the head of the "Happy Go Lucky" toy factory) on Family Guy. It is mentioned in the DVD commentary track that Alazraqui was reluctant to leave the Family Guy series. In particular, Seth McFarlane suggests that the death of Alazraqui's character, Mr. Weed, took the actor by surprise.
In 2005, he added the voices for two Cartoon Network series – The Life and Times of Juniper Lee where he played Monroe, a guardian dog with a Scottish accent and two characters in Camp Lazlo: Lazlo and Clam. In 2006 added Salty Mike from Squirrel Boy and Walden in Wow! Wow! Wubbzy! on Nick Jr. to his credits. He played Wisk in Glen Hill's 2000 film version of L. Frank Baum's The Life and Adventures of Santa Claus. He also provided the voice of Nestor in Happy Feet.
Jeff "Swampy" Marsh, a storyboard writer for Rocko's Modern Life, described Alazraqui's normal voice as bearing "no accent at all". Marsh describes Alazraqui's "Scottish accent" as "one of the best" and that he performs his other accents as "all very well". According to Marsh, Alazraqui uses various accents in his comedy routines.
Alazraqui also does work for the Disney Channel on the Playhouse Disney show Handy Manny. He provides the voice for Felipe, the bilingual Phillips-head screwdriver, and for Abuelito, Manny's grandfather. He was also the original "voice guy" on the Stephanie Miller Show. His replacement was voice actor Jim Ward, who had previously substituted for him. In January 2008, he returned to fill in for Jim Ward briefly while he recovered from surgery.